KLHL1 antibody (10R-2255)

Mouse monoclonal KLHL1 antibody

Synonyms Monoclonal KLHL1 antibody, Anti-KLHL1 antibody, KLHL 1, KLHL 1 antibody, KLHL-1 antibody, KLHL1, KLHL-1 antibody, Kelch like 1 antibody, KLHL 1 antibody, Kelch-like protein 1 antibody, KLHL-1, Kelch-like protein 1 antibody, Mammalian Kelch like 1 antibody
Cross Reactivity Human
Applications ELISA, IF, WB
Immunogen KLHL1 antibody was raised in Mouse using a purified recombinant fragment of human KLHL1 expressed in E. coli as the immunogen.

Images

Immunofluorescent staining using Western Blot analysis using KLHL1 antibody (10R-2255) (KLHL1 antibody)

Immunofluorescence analysis of NIH/3T3 cells using KLHL1 antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Specifications

Host Mouse
Clone 3A8
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IF: 1:200-1:1000, WB: 1:200-1:1000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance KLHL1 was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved in this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Immunofluorescent staining using Western Blot analysis using KLHL1 antibody (10R-2255) (KLHL1 antibody) | Immunofluorescence analysis of NIH/3T3 cells using KLHL1 antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • Western Blot analysis using KLHL1 antibody (10R-2255) | Western Blot showing KLHL1 antibody used against human KLHL1 (AA: 202-506) recombinant protein. (Expected MW is 60.2 kDa)

Availability: In stock

Price: $345.00
Size: 100 ul
OR
Shipping
View Our Distributors