KLHL25 antibody (10R-2204)
Mouse monoclonal KLHL25 antibody
|Synonyms||Monoclonal KLHL25 antibody, Anti-KLHL25 antibody, KLHL25, Ectoderm neural cortex protein 2 antibody, KLHL 25, KLHL-25, ENC2 antibody, KLHL-25 antibody, KLHL 25 antibody|
|Immunogen||KLHL25 antibody was raised in Mouse using a purified recombinant fragment of human KLHL25 expressed in E. coli as the immunogen.|
Western Blot analysis using KLHL25 antibody (10R-2204)
Western Blot showing KLHL25 antibody used against KLHL25 (AA: 2-230)-hIgGFc transfected HEK293 cell.
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||KLHL25 is a cytoplasmic protein that contains six Kelch regions and a single BTB (POZ) domain. KLHL25 is highly homologus to another Kelch-like protein, ENC1, and it is believed to operate in a manner similar to other Kelch-domain containing proteins. Kelch-domain repeat containing proteins often act as modifiers of Actin fibers. Expressed early in embryogenesis, ENC1 helps to mediate neuronal process formation. It also appears to have a role in neural crest cell differentiation. KLHL25 likely functions as a substrate specific adapter for protein ubiquitinating complexes. KLHL25 is expressed in most tissues with highest expression in brain and liver.|
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