KRAS protein (His tag) (80R-2767)

Purified recombinant KRAS protein (His tag)

Synonyms GTPase KRas isoform a precursor protein, C-K-RAS protein, K-RAS2A protein, K-RAS2B protein, K-RAS4A protein, K-RAS4B protein, KI-RAS protein, KRAS1 protein, KRAS2 protein, NS protein, NS3 protein, RASK2 protein, KRAS
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of KRAS protein (His tag) (80R-2767)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-186 aa: MGSSHHHHHH SSGLVPRGSH MGSHMTEYKL VVVGAGGVGK SALTIQLIQN HFVDEYDPTI EDSYRKQVVI DGETCLLDIL DTAGQEEYSA MRDQYMRTGE GFLCVFAINN TKSFEDIHHY REQIKRVKDS EDVPMVLVGN KCDLPSRTVD TKQAQDLARS YGIPFIETSA KTRQRVEDAF YTLVREIRQY RLKKISKEEK TPGCVKIKKC
Expression System E.coli
Purity > 90% pure
Molecular Weight 23.8 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl, 1mM DTT
Concentration 500 ug/ml

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance KRAS is a member of the small GTPase superfamily. This protein is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Under normal conditions, Ras family members influence cell growth and differentiation events in a subcellular membrane compartmentalization-based signaling system. Oncogenic Ras can deregulate processes that control both cell proliferation and apoptosis. Recombinant human KRAS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

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Images

  • SDS-PAGE analysis of KRAS protein (His tag) (80R-2767) | Figure annotation denotes ug of protein loaded and % gel used.
  • SDS-PAGE analysis of KRAS protein (His tag) (80R-2767) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $270.00
Size: 100 ug
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