LAIR1 protein (30R-1033)
Purified recombinant Human LAIR1 protein
|Synonyms||D7Bwg0421e protein, Leukocyte-associated immunoglobulin-like receptor 1 protein, LAIR 1 protein, LAIR-1, LAIR1 protein protein, Lair1 protein, CD305 protein, LAIR-1 (Extracellular domain) protein, Leukocyte associated Ig like receptor 1 protein, Leukocyte-associated immunoglobulin-like receptor 1 isoform a 5133400O11Rik protein, LAIR-1 protein, LAIR 1 protein, CD305 protein protein, LAIR1, LAIR-1 protein, LAIR 1, , mLAIR1 protein, Leukocyte associated immunoglobulin like receptor 1 protein|
Coomassie Blue stained SDS-PAGE of LAIR1 protein (30R-1033)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||Extracellular domain;22-125 amino acids: MQEEDLPRPS ISAEPGTVIP LGSHVTFVCR GPVGVQTFRL ERESRSTYND TEDVSQASPS ESEARFRIDS VSEGNAGPYR CIYYKPPKWS EQSDYLELLV KETSG|
|Purity||> 95% pure|
|Molecular Weight||11.7 kDa (105 aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl, pH7.5, containing 50mM NaCl, and 1mM EDTA.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||LAIR-1 is a glycoprotein (~32kDa) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Lair-1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region. The extracellular domain of LAIR-1 (22-125aa) was overexpressed in E. coli, and purified by using conventional chromatography techniques.|
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