LAL antibody (10R-1955)

Mouse monoclonal LAL antibody

Synonyms Monoclonal LAL antibody, Anti-LAL antibody, Lysosomal acid lipase antibody, LAL antibody, Lysosomal acid lipase antibody, Anti LAL antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen LAL antibody was raised in Mouse using a purified recombinant fragment of LAL expressed in E. coli as the immunogen.

Images

Western Blot analysis using LAL antibody (10R-1955)

Western Blot showing LAL antibody used against LAL recombinant protein.

Specifications

Host Mouse
Clone 9G7F12,7G6D7
Isotype IgG2a
Form & Buffer Purified antibody supplied in PBS containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000,

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance LAL functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.

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Images

  • Western Blot analysis using LAL antibody (10R-1955) | Western Blot showing LAL antibody used against LAL recombinant protein.

Availability: In stock

Price: $295.00
Size: 100 ul
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