Lamin B1 antibody (10R-8083)

Mouse monoclonal Lamin B1 antibody

Synonyms Monoclonal Lamin B1 antibody, Anti-Lamin B1 antibody, Lamin-B1 antibody, LMNB1 antibody, ADLD antibody, LMN antibody, LMN2 antibody, LMNB antibody, MGC111419 antibody, Lamin B1
Specificity Reacts with an epitope located C-terminal of residue 231 in lamin B1
Cross Reactivity Bovine, Canine, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Applications FC, IHC, WB
Immunogen Lamin B1 antibody was raised in Mouse using purified rat liver lamins as the immunogen.


Host Mouse
Clone 119D5-F1
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations FC: 1:100-1:200, IHC: 1:100-1:200, WB: 1:100-1:1000

General Information

Biological Significance Lamins are classified into A and B type isoforms. Specifically, four distinct lamin isoforms have been identified: A, B1, B2, and C. Lamin A and C are alternatively spliced products of a single gene, whereas lamin B1 and B2 are encoded by distinct genes. During mitosis, lamins are phosphorylated by p34cdc2 and solubilized prior to chromosome condensation and nuclear breakdown. A direct role for lamins in chromosome condensation is suggested by the fact that lamin B binds to specific DNA sequence motifs termed matrix attachment regions (MARs).

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Availability: In stock

Price: $389.00
Size: 100 ug
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