Lamin B2 antibody (10R-8084)

Mouse monoclonal Lamin B2 antibody

Synonyms Monoclonal Lamin B2 antibody, Anti-Lamin B2 antibody, LAMB2 antibody, LMN2 antibody, MGC2721 antibody, LMNB2 antibody, Lamin B2
Specificity Reacts with an epitope located in the C-terminal part of lamin B2
Cross Reactivity Hamster, Human, Mouse, Swine, Xenopus, Zebrafish
Applications FC, IHC-F, WB
Immunogen Lamin B2 antibody was raised in Mouse using the detergent insoluble fraction of potoroo cell line PtK1 as the immunogen.

Specifications

Host Mouse
Clone LN43
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations FC: 1:100-1:200, IHC: 1:100-1:200, WB: 1:100-1:1000

General Information

Biological Significance Nuclear lamins, also known as Class V intermediate filaments, are fibrous proteins providing structural function and transcriptional regulation in the cell nucleus. Nuclear lamins interact with membrane-associated proteins to form the nuclear lamina on the interior of the nuclear envelope. They are involved in the breakdown and reformation of the nuclear envelope during mitosis, as well as the positioning of nuclear pores. B-type lamins are present in every cell. B type lamins, B1 and B2, are expressed from the LMNB1 and LMNB2 genes on 5q23 and 19q13, respectively.

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Availability: In stock

Price: $389.00
Size: 100 ug
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