LCK antibody (10R-2019)

Mouse monoclonal LCK antibody

Synonyms Monoclonal LCK antibody, Anti-LCK antibody, YT16 antibody, Lymphocyte-Specific Protein Tyrosine Kinase antibody, YT16 antibody, pp58lck antibody, Anti LCK antibody, pp58lck antibody, Lymphocyte-Specific Protein Tyrosine Kinase antibody, p56lck antibody, LCK antibody, p56lck antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen LCK antibody was raised in Mouse using a purified recombinant fragment of human Lck expressed in E. coli as the immunogen.

Images

Western Blot analysis using LCK antibody (10R-2019)

Western Blot showing LCK antibody used against MOLT-4 (1), CCRF-CEM (2), CCRF-HSB-2 (3) and Jurkat (4) cell lysate.

Specifications

Host Mouse
Clone 8E5F9, 4B2C7
Isotype IgG2a
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance LCK is a member of the Src family of protein tyrosine kinases (PTKs). It is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.

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Images

  • Western Blot analysis using LCK antibody (10R-2019) | Western Blot showing LCK antibody used against MOLT-4 (1), CCRF-CEM (2), CCRF-HSB-2 (3) and Jurkat (4) cell lysate.

Availability: In stock

Price: $375.00
Size: 100 ul
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