LCN2 protein (30R-3192)

Purified recombinant LCN2 protein

Synonyms 25 kDa alpha 2 microglobulin related subunit of MMP 9 protein, Lipocalin 2 protein, Oncogene 24p3 protein, p25 protein, Neutrophil gelatinase associated lipocalin protein, LCN 2 protein, LCN-2 protein
Species Human
Protein Type Recombinant
Applications ELISA, SDS-PAGE, WB

Images

Western blot analysis using LCN2 protein (30R-3192)

Specifications

Expression System E.coli
Purity > 95% pure
Molecular Weight 14 kDa
Form & Buffer Supplied in liquid form in 20mM Tris-Hcl, 0.5MNaCl, 10% glycerin (pH 8.0) and 200 mM Imidazole

Storage & Safety

Storage Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles

General Information

Biological Significance LCN2 is an iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration.

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Images

  • Western blot analysis using LCN2 protein (30R-3192)

Availability: In stock

Price: $210.00
Size: 50 ug
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