LDHA antibody (10R-8620)

Mouse monoclonal LDHA antibody

Synonyms Monoclonal LDHA antibody, Anti-LDHA antibody, LDHA antibody, lactate dehydrogenase A antibody, BOS_24455 antibody, cell proliferation-inducing gene 19 protein antibody, EGK_06433 antibody, GSD11 antibody, l7R2 antibody, lactate dehydrogenase 1 antibody, A chain antibody, lactate dehydrogenase-A antibody, lactate dehydrogenase A1 antibody, lactate dehydrogenase A4 antibody, lactate dehydrogenase A-like antibody, lactate dehydrogenase C antibody, lactate dehydrogenase M antibody, lactate dehydrogenase-M antibody, LDH1 antibody, LDH-A antibody, ldha1 antibody, LDHC antibody, LDHM antibody, LDH-M antibody, LDH muscle subunit antibody, L-lactate dehydrogenase A chain antibody, l-lactate dehydrogenase A chain-like antibody, L-lactic acid dehydrogenase antibody, M(A)-type lactate dehydrogenase antibody, M-LDH antibody, pig19 antibody, proliferation-inducing gene 19 antibody, renal carcinoma antigen NY-REN-59 antibody, upsilon-crystallin antibody
Cross Reactivity Human, Mouse, Rat
Applications ELISA, WB
Immunogen LDHA antibody was raised in Mouse using a recombinant human protein purified from E.coli (His-LDHA) as the immunogen

Images

Western Blot analysis using LDHA antibody (10R-8620)

Specifications

Host Mouse
Clone AF9D1
Isotype IgG1 kappa
Method of Purification LDHA antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Lactate dehydrogenase (LDH) is the enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD+. In mammals, the enzyme is encoded by three genes: LDHA (M or muscle form), LDHB (H or heart form), and LDHC (X or testis form). The three human LDHs have 84?89% sequence similarities and 69?75% amino acid identities. There are five different LDH isoenzymes based on the proportion of M and H chains existing in the LDH tetrameric structure. The LDHA is hypoxia inducible and its expression is directly controlled by the transcriptional activity of the hypoxia inducible factor 1a (HIF1a). LDHB is also known to be upregulated in many cancers.

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Images

  • Western Blot analysis using LDHA antibody (10R-8620) |

Availability: In stock

Price: $295.00
Size: 100 ul
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