LDL Receptor antibody (20R-LR002)

Rabbit polyclonal LDL Receptor antibody

Synonyms Polyclonal LDL Receptor antibody, Anti-LDL Receptor antibody, Low Density Lipoprotein Receptor antibody
Specificity Human LDL receptor
Cross Reactivity To be determined by end-user
Applications FC, IHC, WB
Immunogen LDL receptor antibody was raised in rabbit using a synthetic peptide (sequence not conserved in VLDL receptor and LRP) of the LDL receptor extracellular domain as the immunogen.

Specifications

Host Rabbit
Isotype IgG
Method of Purification Immunoaffinity chromatography
Form & Buffer PBS with 0.5% BSA

Usage & Assay Information

Usage Recommendations FC: 1:10, IHC: 1:20, WB: 1:100-1:200

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Low-density lipoprotein (LDL) is one of the five major groups of lipoproteins, which in order of size, largest to smallest, are chylomicrons, VLDL, IDL, LDL and HDL, that enable lipids like cholesterol and triglycerides to be transported within the water-based bloodstream. Blood tests typically report LDL-C, the amount of cholesterol contained in LDL. In clinical context, mathematically calculated estimates of LDL-C are commonly used to estimate how much low density lipoproteins are driving progression of atherosclerosis. Direct LDL measurements are also available.

References
Add a Paper

Clinica Chimica Acta

Loss-of-function mutation R46L in the PCSK9 gene has little impact on the levels of total serum cholesterol in familial hypercholesterolemia heterozygotes

Clinica Chimica Acta

Volume: 411 Issue: 3-4 Page: 229-233 DOI: 10.1016/j.cca.2009.11.008

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Availability: In stock

Price: $325.00
Size: 250 ul
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