LGALS2 protein (His tag) (80R-1442)
Purified recombinant Human LGALS2 protein
|Synonyms||LGALS-2, LGALS 2, HL14 protein, LGALS 2 protein, LGALS2, S-Lac lectin 2 protein, Galectin2, Beta-galactoside-binding lectin L-14-II protein, LGALS-2 protein, Lactose-binding lectin 2 protein, Gal-2 protein|
Coomassie Blue stained SDS-PAGE of LGALS2 protein (His tag) (80R-1442)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-132 amino acids: MGSSHHHHHH SSGLVPRGSH MTGELEVKNM DMKPGSTLKI TGSIADGTDG FVINLGQGTD KLNLHFNPRF SESTIVCNSL DGSNWGQEQR EDHLCFSPGS EVKFTVTFES DKFKVKLPDG HELTFPNRLG HSHLSYLSVR GGFNMSSFKL KE|
|Purity||> 95% pure|
|Molecular Weight||16.8 kDa (152aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 0.2M NaCl, 1mM DTT and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||LGALS2, also known as galectin 2, is a soluble beta-galactoside binding lectin that modulates cell-to-cell adhesion and cell-to-extracellular matrix interactions and plays a role in tumor progression, pre-mRNA splicing and apoptosis. This protein induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-alpha (LTA) with possible implications in risk of myocardial infarction. Recombinant human Galectin 2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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