LGALS8 protein (His tag) (80R-1450)
Purified recombinant Human LGALS8 protein
|Synonyms||Po66-CBP protein, Gal-8 protein, LGALS-8 protein, LGALS 8, LGALS 8 protein, Prostate carcinoma tumor protein 1 protein, LGALS8, Galectin-8, PCTA1 protein, LGALS-8|
Coomassie Blue stained SDS-PAGE of LGALS8 protein (His tag) (80R-1450)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-317 amino acids: MGSSHHHHHH SSGLVPRGSH MMLSLNNLQN IIYNPVIPFV GTIPDQLDPG TLIVIRGHVP SDADRFQVDL QNGSSMKPRA DVAFHFNPRF KRAGCIVCNT LINEKWGREE ITYDTPFKRE KSFEIVIMVL KDKFQVAVNG KHTLLYGHRI GPEKIDTLGI YGKVNIHSIG FSFSSDLQST QASSLELTEI SRENVPKSGT PQLRLPFAAR LNTPMGPGRT VVVKGEVNAN AKSFNVDLLA GKSKDIALHL NPRLNIKAFV RNSFLQESWG EEERNITSFP FSPGMYFEMI IYCDVREFKV AVNGVHSLEY KHRFKELSSI DTLEINGDIH LLEVRSW|
|Purity||> 90% pure|
|Molecular Weight||37.9 kDa (337aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 0.1M NaCl, 1mM DTT and 10% glycerol.|
Usage & Assay Information
|Bioactivity||The ED50 for this effect is 5 - 10 ug/ml. Measured by its ability to agglutinate human red blood cells|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||LGALS8, also known as prostate-specific membrane protein (PCTA1), is an additional prostate-specific protein that is overexpressed only in malignant tumors and therefore is a more specific identifier of malignancies. It is a member of the galectin gene family which mediates both cell-cell and cell matrix interactions in a manner similar to the selectin subgroup of C-type lectins. Recombinant human LGALS8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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