LOXL1 antibody (70R-5312)

Rabbit polyclonal LOXL1 antibody raised against the N terminal of LOXL1

Synonyms Polyclonal LOXL1 antibody, Anti-LOXL1 antibody, LOXL antibody, LOXL1, LOXL-1 antibody, LOL antibody, LOXL 1 antibody, Lysyl Oxidase-Like 1 antibody, LOXL 1, LOXL-1
Specificity LOXL1 antibody was raised against the N terminal of LOXL1
Cross Reactivity Human,Mouse,Rat
Applications WB
Immunogen LOXL1 antibody was raised using the N terminal of LOXL1 corresponding to a region with amino acids RWRQLIQWENNGQVYSLLNSGSEYVPAGPQRSESSSRVLLAGAPQAQQRR
Assay Information LOXL1 Blocking Peptide, catalog no. 33R-8268, is also available for use as a blocking control in assays to test for specificity of this LOXL1 antibody

Images

Western Blot analysis using LOXL1 antibody (70R-5312)

LOXL1 antibody (70R-5312) used at 1 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 53 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of LOXL1 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance LOXL1 is a member of the lysyl oxidase family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

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Images

  • Western Blot analysis using LOXL1 antibody (70R-5312) | LOXL1 antibody (70R-5312) used at 1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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