LRRC59 protein (His tag) (80R-3055)
Purified recombinant LRRC59 protein (His tag)
|Synonyms||Leucine-rich repeat-containing 59 protein, Leucine rich repeat containing 59 protein, p34 protein, PRO1855 protein, LRRC 59 protein, LRRC-59 protein|
SDS-PAGE analysis of LRRC59 protein (His tag) (80R-3055)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-244 aa: MGSSHHHHHH SSGLVPRGSH MGSMTKAGSK GGNLRDKLDG NELDLSLSDL NEVPVKELAA LPKATILDLS CNKLTTLPSD FCGLTHLVKL DLSKNKLQQL PADFGRLVNL QHLDLLNNKL VTLPVSFAQL KNLKWLDLKD NPLDPVLAKV AGDCLDEKQC KQCANKVLQH MKAVQADQER ERQRRLEVER EAEKKREAKQ RAKEAQEREL RKREKAEEKE RRRKEYDALK AAKREQEKKP KKEANQAPKS KSGSRPRKPP PRKHTRS|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT, 2mM EDTA|
Storage & Safety
|Storage||Store at 4 deg C for short term storage, for long term storage aliquot and store at -20 deg C or -70 deg C, avoid repeated freeze thaw cycles.|
|Biological Significance||LRRC59 is required for nuclear import of FGF1, but not that of FGF2. This proein might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores. Recombinant human LRRC59 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
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