LSD1 antibody (10R-1914)

Mouse monoclonal LSD1 antibody

Synonyms Monoclonal LSD1 antibody, Anti-LSD1 antibody, LSD 1 antibody, LSD-1, LSD 1, LSD 1 antibody, LSD-1 antibody, LSD1, LSD-1 antibody
Cross Reactivity Human, Mouse, Monkey
Applications ELISA, IHC, WB
Immunogen LSD1 antibody was raised in Mouse using a purified recombinant fragment of human LSD1 expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using LSD1 antibody (10R-1914)

Immunohistochemical analysis of paraffin-embedded human lung carcinoma (left) and kidney carcinoma (right), showing nuclear localization using LSD1 antibody with DAB staining.

Specifications

Host Mouse
Clone 1B2E5
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance LSD1 is the first of several protein lysine demethylases discovered. Through a FAD-dependent oxidative reaction, LSD1 speficially removes histone H3K4me2 to H3K4me1 or H3K4me0. When forming a complex with androgen receptor (and possibly other nuclear hormone receptors), LSD1 changes its substrates to H3K9me2. It's now known LSD1 complex mediates a coordinated histone modification switch through enzymatic activities as well as histone modification readers in the complex.

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Images

  • Immunohistochemical staining using LSD1 antibody (10R-1914) | Immunohistochemical analysis of paraffin-embedded human lung carcinoma (left) and kidney carcinoma (right), showing nuclear localization using LSD1 antibody with DAB staining.
  • Western Blot analysis using LSD1 antibody (10R-1914) | Western Blot showing LSD1 antibody used against COS (1), Hela (2), NIH/3T3 (3), A549 (4) and Jurkat (5) cell lysate.

Availability: In stock

Price: $325.00
Size: 100 ul
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