LYN antibody (10R-2103)

Mouse monoclonal LYN antibody

Synonyms Monoclonal LYN antibody, Anti-LYN antibody, LYN antibody, Anti LYN antibody, p53/56 Lyn antibody, p53/56 Lyn antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen LYN antibody was raised in Mouse using a purified recombinant fragment of LYN expressed in E. coli as the immunogen.

Images

Western Blot analysis using LYN antibody (10R-2103)

Western Blot showing LYN antibody agains HL60 (1), L540 (2), SLLP-M2 (3), SEM (4) and Ramos (5) cell lysate.

Specifications

Host Mouse
Clone 2H8D7
Isotype IgG2b
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Lyn is a membrane associated protein tyrosine kinase (PTK) mostly expressed in hemopoietic cells which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis. A member of the Src family of PTKs, there are two known isoforms for Lyn which plays an indispensable role in the Fc epsilon RI (Fcer1) and the B cell IgM receptor signaling pathway and is essential for Syk activation and Lat phosphorylation after Fcer1 aggregation and can also phosphorylate Tec on multiple residues.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Blot analysis using LYN antibody (10R-2103) | Western Blot showing LYN antibody agains HL60 (1), L540 (2), SLLP-M2 (3), SEM (4) and Ramos (5) cell lysate.

Availability: In stock

Price: $375.00
Size: 100 ul
OR
Shipping
View Our Distributors