LYN antibody (10R-2103)
Mouse monoclonal LYN antibody
|Synonyms||Monoclonal LYN antibody, Anti-LYN antibody, LYN antibody, Anti LYN antibody, p53/56 Lyn antibody, p53/56 Lyn antibody|
|Immunogen||LYN antibody was raised in Mouse using a purified recombinant fragment of LYN expressed in E. coli as the immunogen.|
Western Blot analysis using LYN antibody (10R-2103)
Western Blot showing LYN antibody agains HL60 (1), L540 (2), SLLP-M2 (3), SEM (4) and Ramos (5) cell lysate.
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Lyn is a membrane associated protein tyrosine kinase (PTK) mostly expressed in hemopoietic cells which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis. A member of the Src family of PTKs, there are two known isoforms for Lyn which plays an indispensable role in the Fc epsilon RI (Fcer1) and the B cell IgM receptor signaling pathway and is essential for Syk activation and Lat phosphorylation after Fcer1 aggregation and can also phosphorylate Tec on multiple residues.|
Sorry, but there are no references currently for this product.
Sorry there are currently no reviews for this product