MAGE antibody (10R-8090)

Mouse monoclonal MAGE antibody

Synonyms Monoclonal MAGE antibody, Anti-MAGE antibody, Melanoma associated antigen antibody, MAGE
Cross Reactivity Human
Applications ELISA, IF, IHC-F, IHC-P
Immunogen MAGE antibody was raised in Mouse using a predominantly intracellular protein of human melanoma cells as the immunogen.

Specifications

Host Mouse
Clone NKI-C3
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations Optimal dilution should be determined by titration

General Information

Biological Significance The mammalian members of the MAGE (melanoma-associated antigen) gene family were originally described as completely silent in normal adult tissues, with the exception of male germ cells and, for some of them, placenta. By contrast, these genes were expressed in various kinds of tumors. MAGE-like genes have also been identified in non-mammalian species, like the zebrafish or Drosophila melanogaster. Although no MAGE homologous sequences have been identified in Caenorhabditis elegans, Saccharomyces cerevisiae or Schizosaccharomyces pombe, MAGE sequences have been found in several vegetal species, including Arabidopsis thaliana. The only region of homology shared by all of the members of the family is a stretch of about 200 amino acids which has been named the MAGE conserved domain.

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Availability: In stock

Price: $425.00
Size: 100 ug
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