MAGEA6 protein (His tag) (80R-2301)
Purified recombinant Human MAGEA6 Protein (His tag)
|Synonyms||MAGE6 protein, MAGEA-6, CT1.6 protein, MAGEA 6, MAGEA-6 protein, MAGEA 6 protein, MAGE3B protein, MAGEA6, MAGE-3b protein|
Coomassie Blue stained SDS-PAGE of MAGEA6 protein (His tag) (80R-2301)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MPLEQRSQHC KPEEGLEARG EALGLVGAQA PATEEQEAAS SSSTLVEVTL GEVPAAESPD PPQSPQGASS LPTTMNYPLW SQSYEDSSNQ EEEGPSTFPD LESEFQAALS RKVAKLVHFL LLKYRAREPV TKAEMLGSVV GNWQYFFPVI FSKASDSLQL VFGIELMEVD PIGHVYIFAT CLGLSYDGLL GDNQIMPKTG FLIIILAIIA KEGDCAPEEK IWEELSVLEV FEGREDSIFG DPKKLLTQYF VQENYLEYRQ VPGSDPACYE FLWGPRALIE TSYVKVLHHM VKISGGPRIS YPLLHEWALR EGEELEHHHH HH|
|Purity||> 90% pure|
|Molecular Weight||35.9 kDa|
|Form & Buffer||Supplied in liquid form in 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||MAGEA6 is a member of the MAGEA family, which directs the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes . The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. Recombinant human MAGEA6 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
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