MAPK14 antibody (Thr180/Tyr182) (70R-15038)

Rabbit polyclonal MAPK14 antibody (Thr180/Tyr182)

Synonyms Polyclonal MAPK14 antibody, Anti-MAPK14 antibody, MAPK 14 antibody, MAPK-14 antibody, MAPK14, CSAID Binding Protein 1 antibody, CSAID binding protein antibody, CSAID-binding protein antibody, Csaids binding protein antibody, CSBP 1 antibody, CSBP 2 antibody, CSBP antibody, CSBP1 antibody, CSBP2 antibody, CSPB 1 antibody, CSPB1 antibody, Cytokine suppressive anti inflammatory drug binding protein antibody, Cytokine suppressive anti-inflammatory drug-binding protein antibody, EXIP antibody, MAP kinase 14 antibody, MAP kinase MXI2 antibody, MAP kinase p38 alpha antibody, MAPK 14 antibody, MAPK14 antibody, MAX interacting protein 2 antibody, MAX-interacting protein 2 antibody, Mitogen Activated Protein Kinase 14 antibody, Mitogen activated protein kinase p38 alpha antibody, Mitogen-activated protein kinase 14 antibody, Mitogen-activated protein kinase p38 alpha antibody, Mxi 2 antibody, Mxi2 antibody, p38 ALPHA antibody, p38 MAP kinase antibody, p38 MAPK antibody, p38 mitogen activated protein kinase antibody, p38ALPHA antibody, p38alpha Exip antibody, PRKM14 antibody, PRKM15 antibody, RK antibody, SAPK 2A antibody, SAPK2A antibody, Stress Activated Protein Kinase 2A antibody
Applications IHC, WB

Images

Immunohistochemical staining using MAPK14 antibody (Thr180/Tyr182) (70R-15038)

Immunohistochemical staining of human breast cancer tissue showing p38 when phosphorylatedat Thr180/Tyr182 in red.

Specifications

Host Rabbit
Method of Purification MAPK14 antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

General Information

Biological Significance The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

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Images

  • Immunohistochemical staining using MAPK14 antibody (Thr180/Tyr182) (70R-15038) | Immunohistochemical staining of human breast cancer tissue showing p38 when phosphorylatedat Thr180/Tyr182 in red.
  • Western Blot analysis using MAPK14 antibody (Thr180/Tyr182) (70R-15038) | Western blot of HeLa celllysates that had been treated with UV or untreated (Control) showing specific immunolabeling of ~39k p38 MAPK protein phosphorylated at Thr180/Tyr182

Availability: In stock

Price: $335.00
Size: 100 ul
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