MARCKS antibody (20R-2858)

Rabbit polyclonal MARCKS antibody

Synonyms Polyclonal MARCKS antibody, Anti-MARCKS antibody, Myristoylated alanine-rich protein kinase C substrate antibody, 80K-L antibody, FLJ14368 antibody, FLJ90045 antibody, MACS antibody, PKCSL antibody, PRKCSL antibody
Applications IF, WB

Images

Immunofluorescent staining using MARCKS antibody (20R-2858)

Mixed neuron/glial cultures stained with MARCKS antibody (red) and MAP2 (green)

Specifications

Host Rabbit
Form & Buffer Supplied as a Neat Serum

Usage & Assay Information

Usage Recommendations WB: 1:10000, IF: 1:500

General Information

Biological Significance The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

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Images

  • Immunofluorescent staining using MARCKS antibody (20R-2858) | Mixed neuron/glial cultures stained with MARCKS antibody (red) and MAP2 (green)
  • Western Blot analysis using MARCKS antibody (20R-2858) | Western blot of rat cortex lysate showing specific immunolabeling of ~80kMARCKS protein

Availability: In stock

Price: $295.00
Size: 100 ul
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