MCP1 protein (Mouse) (30R-AJ001)

Purified recombinant Mouse MCP1 protein

Synonyms MCP-1 protein, MCP 1, MCP1, MCP-1 protein, MCP-1 protein, MCP 1 protein, Monocyte Chemotactic Protein-1 protein, MCP-1, CCL2 protein
Species Mouse
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of MCP1 protein corresponding to amino acids QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN.
Expression System E.coli
Purity > 98% pure
Molecular Weight 13.8 kDa
Form & Buffer Supplied lyophilized with no additives. Reconstitute in sterile water to 0.1-1.0 mg/ml. Allow to set for at least 30 minutes.

Usage & Assay Information

Bioactivity Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species.

References
Add a Paper

Elisabeth Frøylanda, Elena Didenko Pedersenb, Anne-Katrine Kvisselc, Runar Almaasd, Anne Pharob, Bjørn Steen Skålhegge, Tom Eirik Mollnesb, Terje Rootwelt

Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons

Brain Research

Volume: 1113 Issue: 1 Page: 64-73 DOI: 10.1016/j.brainres.2006.07.051

O. Bogen, O.A. Dina1, R.W. Gear, J.D. Levine

Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican

Neuroscience

Volume: 159 Issue: 2 Page: 780-786 DOI: 10.1016/j.neuroscience.2008.12.049

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Availability: In stock

Price: $225.00
Size: 10 ug
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