MDC protein (Mouse) (30R-AM058)

Purified recombinant Mouse MDC protein

Synonyms STCP-1 protein, CCL22 protein, Macrophage-Derived Chemokine protein, ABCD-1 protein
Species Mouse
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of MDC protein corresponding to amino acids GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS.
Expression System E.coli
Purity > 98% pure
Molecular Weight 7.8 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Determined by its ability to chemoattract human activated lymphoytes using a concentration of 10.0-100.0 ng/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity.

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Availability: In stock

Price: $225.00
Size: 20 ug
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