MEK1 antibody (10R-8531)

Mouse monoclonal MEK1 antibody

Synonyms Monoclonal MEK1 antibody, Anti-MEK1 antibody, MAP2K1 antibody, mitogen-activated protein kinase kinase 1 antibody, BOS_10196 antibody, CH73-94F11.4 antibody, dual specificity mitogen activated protein kinase kinase 1 antibody, dual specificity mitogen-activated protein kinase kinase 1 antibody, EGK_17610 antibody, ERK activator kinase 1 antibody, map2k2 antibody, MAPK/ERK kinase 1 antibody, MAP kinase/Erk kinase 1 antibody, MAP kinase kinase 1 antibody, MAP kinase kinase or Erk Kinase antibody, Dual specificity mitogen-activated protein kinase kinase antibody, involved in ras mediated vulval induction antibody, LEThal LET-537 (42.8 kD) (mek-2) antibody, mapkk1 antibody, MAPKK 1 antibody, MEK antibody, mek1 antibody, MEK 1 antibody, mek-2 antibody, MEKK1 antibody, mitogen activated protein kinase kinase 1 antibody, mkk1 antibody, PANDA_002194 antibody, PRKMK1 antibody, protein kinase antibody, mitogen-activated antibody, kinase 1 (MAP kinase kinase 1) antibody, protein kinase antibody, mitogen activated antibody, kinase 1 antibody, p45 antibody, RCJMB04_27f19 antibody
Cross Reactivity Human, Mouse, Rat
Applications ELISA, WB
Immunogen MEK1 antibody was raised in Mouse using a recombinant human protein purified from E.coli(His-MEK1) as the immunogen

Images

Western Blot analysis using MEK1 antibody (10R-8531)

Specifications

Host Mouse
Clone 32G3
Isotype IgG1 kappa
Method of Purification MEK1 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance The human MEK1 encodes 393 amino acid residues and shares 99% amino acid sequence identity with the murine MEKl and 80% with human MEK2 (400 amino acids). The MEKs constitute an evolutionarily conserved group of three highly homologous mammalian isoforms. These are the 45 kDa MEK1, its alternatively spliced form, MEK1b (43 kDa) that is thought to be inactive, and the 46 kDa MEK2. These proteins are composed of a catalytic kinase domain, which is surrounded by a regulatory N-terminal domain ( 80 amino acids) and a shorter C-terminal region ( 30 amino acids). MEKs are activated by phosphorylation of two Ser residues in their activation loop (Ser218 and Ser222 in MEK1). The activity of MEKs is regulated by additional phosphorylation/dephosphorylation processes as well.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Blot analysis using MEK1 antibody (10R-8531) |

Availability: In stock

Price: $295.00
Size: 100 ul
OR
Shipping
View Our Distributors