MEK3 antibody (10R-8542)

Mouse monoclonal MEK3 antibody

Synonyms Monoclonal MEK3 antibody, Anti-MEK3 antibody, MAP2K3 antibody, mitogen-activated protein kinase kinase 3 antibody, BOS_18787 antibody, dual specificity mitogen-activated protein kinase kinase 3 antibody, MAPK/ERK kinase 3 antibody, MAP kinase activator XMEK3 antibody, MAP kinase kinase 3 antibody, MAPKK3 antibody, MAPKK 3 antibody, MEK3 antibody, MEK 3 antibody, mitogen activated protein kinase kinase 3 antibody, MKK3 antibody, mMKK3b antibody, Prkmk3 antibody, protein kinase antibody, mitogen-activated antibody, kinase 3 antibody, RCJMB04_8f10 antibody, RP23-467E19.1 antibody, SAPKK2 antibody, SAPKK-2 antibody, SAPK kinase 2 antibody, stress-activated protein kinase kinase 2 antibody
Cross Reactivity Human, Mouse, Rat
Applications WB
Immunogen MEK3 antibody was raised in Mouse using a recombinant human protein purified from E.coli (His-MEK3) as the immunogen

Images

Western Blot analysis using MEK3 antibody (10R-8542)

Specifications

Host Mouse
Clone 3G2
Isotype IgG2a kappa
Method of Purification MEK3 antibody was purified by IgG purification
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance The human MEK3 encodes 347 amino acid residues. MEKs (MEK1, MEK2, MEK3) show remarkably different activity toward ERKl and ERK2. MEK2 is the most active ERK activator. MEK3 is inactive toward ERKl or ERK2. MEK3, MEK4, and MEK6 phosphorylate and activate p38 MAP kinase. The p38 mitogen-activated protein (MAP) kinase signal transduction pathway is activated by proinflammatory cytokines and environmental stress. Transcription factors such as ATF2 and Elk-1 are targets of the p38 MAP kinase signal transduction pathway.

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Images

  • Western Blot analysis using MEK3 antibody (10R-8542) |

Availability: In stock

Price: $295.00
Size: 100 ul
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