Methionine Sulfoxide Reductase A protein (30R-3003)

Purified recombinant Methionine Sulfoxide Reductase A protein

Synonyms Methionine Sulfoxide Reductase A protein, cytosolic methionine-S-sulfoxide reductase protein, Methionine sulphoxide reductase A protein, MSR A protein, MSRA protein, peptide met (O) reductase protein, Peptide methionine (S) S oxide reductase protein, PMSR protein, Protein methionine S oxide reductase protein
Species Human
Protein Type Recombinant
Applications WB

Images

Western Blot analysis using Methionine Sulfoxide Reductase A protein (30R-3003)

Specifications

Expression System E.coli
Purity > 95% pure
Molecular Weight 28 kDa
Form & Buffer Supplied in liquid form in 20mM HEPES, pH 7.0, 10% Glycerol
Concentration 1mg/ml

Usage & Assay Information

Bioactivity 36 U/mg (One unit will cause the oxidation of 1umole of NADPH at 30 deg C at pH 7.4)

Storage & Safety

Storage Store at -80 deg C. Avoid frequent freeze/thaw cycles

General Information

Biological Significance Methione sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system, MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimers disease in mammals.

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Images

  • Western Blot analysis using Methionine Sulfoxide Reductase A protein (30R-3003) |

Availability: In stock

Price: $265.00
Size: 100 ug
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