MLL antibody (70R-14307)

Affinity purified Mouse polyclonal MLL antibody

Synonyms Polyclonal MLL antibody, Anti-MLL antibody, Trithorax-like protein antibody, HRX antibody, Myeloid/lymphoid leukemia antibody, Lysine N-methyltransferase 2A antibody, ALL-1 antibody, ALL 1 antibody, Zinc finger protein HRX antibody
Applications WB
Immunogen MLL antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human MLL, identical to the related Rabbit sequence as the immunogen

Specifications

Host Rabbit
Isotype IgG
Method of Purification MLL antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance MLL contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes.

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Availability: In stock

Price: $270.00
Size: 100 ug
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