MMP3 antibody (10R-M114b)

Mouse monoclonal MMP3 antibody

Synonyms Monoclonal MMP3 antibody, Anti-MMP3 antibody, MMP-3 antibody, MMP3, Matrix Metalloproteinase 3 antibody, MMP-3, MMP 3 antibody, MMP 3, MMP 3 antibody, Stromelysin 1 antibody, MMP-3 antibody
Specificity Human
Cross Reactivity To be determined by end-user
Applications IF, WB
Immunogen MMP3 antibody was raised in mouse using APMA (4-Aminophenylmercuric acetate) activated human stromelysin-1 (SL-1) as the immunogen.

Specifications

Host Mouse
Clone SL-1 IID4
Isotype IgG2b
Method of Purification MMP3 antibody was purified by Protein A chromatography.
Molecular Weight 54 kDa (predicted detection band MW)/59 kDa (pro form), 44 kDa (predicted detection band MW)/49 kDa (active form)
Form & Buffer Antibody purified from ascites fluid by protein G chromotography and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
Concentration 0.2 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.5-1.0 ug/ml

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading connective tissue components. Imbalanced secretion of certain MMP or disturbances in the differential control of MMP by tissue inhibitor of MMPs (TIMPs) are implicated in the invasive potential of malignant tumors. Stromelysin (MMP3 / Transin) degrades several matrix components including the core proteins of proteoglycans, laminin and nonhelical regions of collagens.

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Availability: In stock

Price: $484.00
Size: 100 ug
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