Mouse GCSF ELISA Kit (55R-1580)

ELISA Kit for detection of GCSF in the research laboratory

Synonyms Mouse GCSF ELISA kit, Granulocyte Colony-Stimulating Factor ELISA kit, CSF3 ELISA kit, MGI1G ELISA kit, GMCSFb ELISA kit, Pluripoietin ELISA kit
Applications ELISA
Assay Information Sensitivity: 31.2 pg/ml-2000 pg/ml

Images

ELISA assay using Mouse GCSF ELISA Kit (55R-1580)

Graph showing ELISA absorbance curve (O.D.) of Mouse G-CSF (pg/ml)

Specifications

Form & Buffer This Kit contains: Lyophilized recombinant Mouse G-csf standard: 10ng/tube

Storage & Safety

Storage Store at 4 deg C for short term storage (4 months) or -20 deg C for long term storage (8 months)

General Information

Biological Significance Granulocyte colony-stimulating factor (G-CSF) is a member of the CSF family of hormone-like glycoprotein that regulates hematopoietic cell proliferation and differentiation, and it almost exclusively stimulates the colony formation of granulocytes from committed precursor cells in semi-solid agar culture.1 G-CSF is also termed colony stimulating factor-3, and a single gene of which codes for a 177 or 180 amino acid mature protein of molecular weight 19,600. Functionally, it specifically stimulates the proliferation and differentiation of the progenitor cells for granulocytes. The effect of G-CSF on myeloid leukemias is unique among colony stimulating factors in driving the leukemic cells from a self-renewing malignant state to a mature differentiated phenotype with the concomitant loss of tumorigenicity.2 Besides, it also prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes. The recombinant form of hG-CSF is capable of supporting neutrophil proliferation in a CFU-GM assay as well as early erythroid colonies and mixed colony formation. Human gene coding for G-CSF is assigned to the q21-q22 region of chromosome 17.3 The standard product used in this kit is recombinant Mouse G-csf, consisting of 179 amino acids with the molecular mass of 19 kDa.

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Images

  • <div><font face=Calibri size=2>ELISA assay using Mouse GCSF ELISA Kit (55R-1580)</font></div>     | Graph showing ELISA absorbance curve (O.D.) of Mouse G-CSF (pg/ml)

Availability: In stock

Price: $415.00
Size: 1 kit
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