Mouse IL1 beta ELISA kit (55R-1607)

ELISA kit for the detection of Mouse IL1 beta in the research laboratory

Synonyms Mouse IL1 beta ELISA kit, Interleukin 1 beta ELISA kit, Catabolin ELISA kit, Lymphocyte-activating Factor ELISA kit, Leukocyte Endogenous Mediator ELISA kit, LEM ELISA kit, Mononuclear Cell Factor ELISA kit, MCF ELISA kit
Applications ELISA
Assay Information Sensitivity: 7.8 pg/ml-500 pg/ml

Images

ELISA assay using Mouse IL1 beta ELISA kit (55R-1607)

Graph showing ELISA absorbance curve (O.D.) of Mouse IL1beta (pg/ml)

Specifications

Form & Buffer This Kit contains: Lyophilized recombinant mouse IL-1

Storage & Safety

Storage Store at 4 deg C for short term storage (4 months) or -20 deg C for long term storage (8 months)

General Information

Biological Significance Interleukin1 (IL1), originally described in 1972 as lymphocyte activating factor (LAF) for its effects on thymocytes, is a polypeptide cytokine with two molecular forms. Both forms appear to mediate identical ranges of biological activity which include synthesis of the acute phase proteins by hepatocytes, chemotaxis of polymorphonucleocytes, and release of polymorphonucleocytes from blood and bone marrow. These effects coined the acronym leukocyte endogenous mediator (LEM). Early researchers also called IL1 beta endogenous pyrogen, and it has been shown to induce fever and is thought to contribute to wasting of muscles (PIF, proteolysis inducing factor). Other activities associated with IL1 are the induction of Prostaglandin E2 by synovial cells and release of collagenase with resulting destruction of cartilage and bone resorption (catabolin, osteoclast activation factor). In addition, IL1 has multiple immunological functions including enhancement of IL2 production by T cells and activation of B cells (BAF) and thymocytes. A true pleiotrope, IL1 may have tumoricidal activity via its release of IL2 and interferon gamma and be indirectly antiviral by stimulating fibroblasts to release interferon beta. In its role as mediator of sepsis, IL1 has most recently been described as enhancing the growth of virulent E. coli.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • <div><font face=Calibri size=2>ELISA assay using Mouse IL1 beta ELISA kit (55R-1607)</font></div>     | Graph showing ELISA absorbance curve (O.D.) of Mouse IL1beta (pg/ml)

Availability: In stock

Price: $460.00
Size: 1 kit
OR
Shipping
View Our Distributors