Mouse MMP9 ELISA kit (55R-1656)

ELISA kit for the detection of MMP9 in the research laboratory

Synonyms Human MMP9 ELISA kit, Matrix Metalloproteinase 9 ELISA kit
Applications ELISA
Assay Information Sensitivity: 156 pg/ml-10,000 pg/ml

Images

ELISA assay using Mouse MMP9 ELISA kit (55R-1656)

Graph showing ELISA absorbance curve (O.D.) of Mouse MMP9 (pg/ml)

Specifications

Form & Buffer This Kit contains: Lyophilized recombinant mouse MMP-9 standard: 10ng/tube

Storage & Safety

Storage Store at 4 deg C for short term storage (4 months) or -20 deg C for long term storage (8 months)

General Information

Biological Significance Matrix metalloproteinases (MMPs) form a family of enzymes with major actions in the remodelling of extracellular matrix (ECM) components. MMP9, also called Gelatinase B, is the most complex family member in terms of domain structure and regulation of its activity. MMP9 activity is under strict control at various levels: transcription of the gene by cytokines and cellular interactions; activation of the proenzyme by a cascade of enzymes comprising serine proteases and other MMPs; and regulation by specific tissue inhibitors of MMPs (TIMPs) or unspecific inhibitors. Further glycosylation has a limited effect on the net activity of Gelatinase B and chemotactic factors are another level of control of activity. The main function of MMPs is degradation of the extracellular physiologic function including wound healing, bone resorption and mammary involution. MMPs also contribute to pathological conditions such as rheumatoid arthritis, coronary artery disease and cancer. They are thought to promote the growth of these tumor cells once they have metastasized. MMP9 plays an important role in tumor invasion, angiogenesis and metastasis.

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  • <div><font face=Calibri size=2>ELISA assay using Mouse MMP9 ELISA kit (55R-1656)</font></div>     | Graph showing ELISA absorbance curve (O.D.) of Mouse MMP9 (pg/ml)

Availability: In stock

Price: $475.00
Size: 1 kit
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