Mouse OPG ELISA kit (55R-1665)

ELISA kit for the detection of OPG in the research laboratory

Synonyms Human OPG ELISA kit, Osteoprotegerin ELISA kit, Osteoclastogenesis Inhibitory Factor ELISA kit, TR1 protein ELISA kit
Applications ELISA
Assay Information Sensitivity: 93.8 pg/ml-6000 pg/ml

Images

ELISA assay using Mouse OPG ELISA kit (55R-1665)

Graph showing ELISA absorbance curve (O.D.) of Mouse OPG (pg/ml)

Specifications

Form & Buffer This Kit contains: Lyophilized recombinant mouse OPG standard: 10ng/tube

Storage & Safety

Storage Store at 4 deg C for short term storage (4 months) or -20 deg C for long term storage (8 months)

General Information

Biological Significance Osteoprotegerin (OPG) or osteoclastogenesis inhibitory factor (OCIF) is a secretory glycoprotein belonging to TNF receptor superfamily. OPG consists of 401 amino acid residues, it has a molecular weight of 60 kDa as a monomer and 120 kDa as a disulfidelinked dimer and is produced in different tissues, e.g. bone, skin, liver, stomach, intestine and lung. Osteoprotegerin inhibits the binding of RANK to RANKL (TRANCE, osteoprotegerin ligand, OPGL, osteoclast differentiation factor, ODF) and thus inhibits the recruitment, proliferation and activation of osteoclasts. Since OPG exhibits an inhibitory effect on osteoclasts, it acts as a soluble factor in the regulation of bone mass. Osteoclast formation activity may be monitored principally by determination of concentration ratio of OPGL/OPG. Alteration of this ratio may be the cause of bone loss in many imbalances in bone metabolism such as osteoporosis, osteopetrosis,hypercalcemia, metastatic osteolytic lesions and rheumatic bone degradation.

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Images

  • <div><font face=Calibri size=2>ELISA assay using Mouse OPG ELISA kit (55R-1665)</font></div>     | Graph showing ELISA absorbance curve (O.D.) of Mouse OPG (pg/ml)

Availability: In stock

Price: $415.00
Size: 1 kit
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