MPZL1 protein (His tag) (80R-2931)

Purified recombinant NSMCE1 protein (His tag)

Synonyms Myelin protein zero-like 1 isoform b protein, MPZL1b protein, PZR protein, PZR1b protein, PZRa protein, PZRb protein, MPZL 1 protein, MPZL-1 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of MPZL1 protein (His Tag) (80R-2931)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 38-162 aa: MGSSHHHHHH SSGLVPRGSH MGSLEVYTPK EIFVANGTQG KLTCKFKSTS TTGGLTSVSW SFQPEGADTT VSFFHYSQGQ VYLGNYPPFK DRISWAGDLD KKDASINIEN MQFIHNGTYI CDVKNPPDIV VQPGHIRLYV VEKENLPV
Expression System E.coli
Purity > 90% pure
Molecular Weight 16.1 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Concentration 500 ug/ml

Storage & Safety

Storage Store at 4 deg C for up to 2 weeks. For long term storage, aliquot and store at -20 deg C to -70 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance MPZL1 is a cell surface receptor, which is involved in signal transduction processes. This protein recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. It is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

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Images

  • SDS-PAGE analysis of MPZL1 protein (His Tag) (80R-2931) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $375.00
Size: 50 ug
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