MRP antibody (10R-2353)

Mouse monoclonal MRP antibody

Synonyms Monoclonal Multidrug Resistance Associated Protein antibody, Anti Multidrug Resistance Associated Protein antibody, Multidrug Resistance Associated Protein antibody, MRP antibody, Anti Multidrug Resistance Associated Protein antibody, MRP antibody
Cross Reactivity Mouse
Applications FC, IHC, WB
Immunogen Multidrug Resistance Associated Protein antibody was raised in rat using Bacterial fusion protein containing 168 aa (aa 192-360) in the amino proximal half of MRP1 as the immunogen.

Specifications

Host Rat
Clone MWPr1
Isotype IgG2a
Form & Buffer Supplied in liquid form. Dilute with with PBS with 1% BSA and 0.1% Na-Azide
Concentration 20 ug/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance MRP is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. More specifically, this protein is a member of the MRP subfamily, which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells.

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Availability: In stock

Price: $703.00
Size: 500 ul
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