MSH6 antibody (10R-2166)

Mouse monoclonal MSH6 antibody

Synonyms Monoclonal MSH6 antibody, Anti-MSH6 antibody, Muts Homolog 6 antibody, GTBP antibody, MSH 6, MSH-6 antibody, HNPCC5 antibody, MSH-6, MSH 6 antibody, HSAP antibody, MSH6
Cross Reactivity Human
Applications ELISA, WB
Immunogen MSH6 antibody was raised in Mouse using a purified recombinant fragment of MSH6 expressed in E. coli as the immunogen.

Images

Western Blot analysis using MSH6 antibody (10R-2166)

Western Blot showing MSH6 antibody used against truncated MSH6 recombinant protein.

Specifications

Host Mouse
Clone 3A10H7
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.

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Images

  • Western Blot analysis using MSH6 antibody (10R-2166) | Western Blot showing MSH6 antibody used against truncated MSH6 recombinant protein.

Availability: In stock

Price: $345.00
Size: 100 ul
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