MSK2 antibody (20R-2905)

Rabbit polyclonal MSK2 antibody

Synonyms Polyclonal MSK2 antibody, Anti-MSK2 antibody, RPS6KA4 antibody, ribosomal protein S6 kinase antibody, 90kDa antibody, polypeptide 4 antibody, 90kDa antibody, 90 kDa ribosomal protein S6 kinase 4 antibody, BOS_24868 antibody, Ccdc88b antibody, coiled-coil domain containing 88B antibody, DKEY-273O13.5 antibody, mitogen- and stress-activated protein kinase 2 antibody, mitogen- and stress-activated protein kinase-2 antibody, mMSK2 antibody, Msk2 antibody, nuclear mitogen- and stress-activated protein kinase 2 antibody, ribosomal protein kinase B antibody, ribosomal protein S6 kinase antibody, 90kD antibody, polypeptide 4 antibody, ribosomal protein S6 kinase alpha 4 antibody, ribosomal protein S6 kinase alpha-4 antibody, ribosomal protein S6 kinase antibody, polypeptide 4 antibody, RLSK antibody, RSKB antibody, RSK-B antibody, RSK-like protein kinase antibody, S6K-alpha-4 antibody
Cross Reactivity Human
Applications IHC-P, WB
Immunogen MSK2 antibody was raised in Rabbit using a synthetic target peptide as the immunogen

Images

Western Blot analysis using MSK2 antibody (20R-2905)

Specifications

Host Rabbit
Isotype IgG
Method of Purification MSK2 antibody was purified by Protein A affinity chromatography
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Mitogen- and stress-activated protein kinases (MSK2) is nuclear kinase that act downstream of mitogen-activated protein/extracellular signal-regulated kinase pathways. It contains two kinase domains in the N-terminal and C-terminal region, respectively. MSK2 is activated in response to mitogenic stimuli via Erk1/2MAPK pathway and also by stress stimuli via p38MAPK pathway. Signals from mitogens and cellular stresses are involved in many functions including cell proliferation, differentiation, and survival through the phosphorylation of cyclic AMP response element-binding protein (CREB) at Ser133 which is catalyzed by MSK2.

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Images

  • Western Blot analysis using MSK2 antibody (20R-2905) |

Availability: In stock

Price: $295.00
Size: 100 ul
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