MST1R antibody (10R-2002)
Mouse monoclonal MST1R antibody
|Synonyms||Monoclonal MST1R antibody, Anti-MST1R antibody, cdw136 antibody, MSTR-1 antibody, CD136 antigen antibody, fv2 antibody, Cluster of differentiation 136 antibody, MSTR-1, MSTR 1, MSTR 1 antibody, Friend virus susceptibility 2 antibody, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) antibody, MST1R|
|Immunogen||MST1R antibody was raised in Mouse using a purified recombinant fragment of human MST1R (aa210-320) expressed in E. coli as the immunogen.|
Western Blot analysis using MST1R antibody (10R-2002)
Western Blot showing RON antibody used against HCC827 (1), HT-29 (2), HCT-116 (3) and BxPC-3 (4) cell lysate.
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||MST1R is a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kDa (alpha) and 150-kDa (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain.|
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