MUC1 antibody (10R-8091)

Mouse monoclonal MUC1 antibody

Synonyms Monoclonal MUC1 antibody, Anti-MUC1 antibody, MUC-1 antibody, MUC 1 antibody, Mucin-1 antibody, CD227 antibody, MUC1
Specificity React with a peptide epitope in the repeat region of MUC-1
Cross Reactivity Human
Applications ELISA, FC, IF, IHC-F, IP, WB
Immunogen MUC1 antibody was raised in Mouse using human milk-fat globule membranes (HMFGM) as the immunogen.

Specifications

Host Mouse
Clone 139H2
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations Optimal dilution should be determined by titration

General Information

Biological Significance Mucins are heavily glycosylated proteins which constitute the major components of mucus covering the surface of epithelial tissues. Nine distinct epithelial mucin genes (Muc-1, 2, 3, 4, 5AC, 5B, 6, 7 and 8) have been identified. Various immunohistochemical and in situ hybridization studies have reported that these mucins are differentially expressed in epithelia with cell-type specificity. In gastric cancer, alterations in mucin polypeptide expression have been reported, including the loss of expression of Muc-5AC glycoprotein, increased mucin heterogeneity, glycosylation changes and the expression of simple mucin-type carbohydrates.

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Availability: In stock

Price: $395.00
Size: 100 ug
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