MUC1 antibody (10R-8092)

Mouse monoclonal MUC1 antibody

Synonyms Monoclonal MUC1 antibody, Anti-MUC1 antibody, MUC-1 antibody, MUC 1 antibody, Mucin-1 antibody, CD227 antibody, MUC1
Specificity Reacts with a carcinoma-associated antigen in both adenocarcinomas and squamous cell carcinomas of different origins
Cross Reactivity Human
Applications ELISA, FC, IF, IHC-F, IP, WB
Immunogen MUC1 antibody was raised in Mouse using human milk-fat globule membranes (HMFGM) as the immunogen.

Specifications

Host Mouse
Clone 175C5
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations Optimal dilution should be determined by titration

General Information

Biological Significance Mucin 1, cell surface associated (MUC-1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC-1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with colon, breast, ovarian, lung and pancreatic cancers.

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Availability: In stock

Price: $395.00
Size: 100 ug
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