MXI1 antibody (10R-1598)

Mouse monoclonal MXI1 antibody

Synonyms Monoclonal MXI1 antibody, Anti-MXI1 antibody, MXI1, MXI-1, MXD2 antibody, MAX interacting protein 1 antibody, MXI 1 antibody, MAD2 antibody, MXI antibody, MXI-1 antibody, MGC43220 antibody, MXI 1
Specificity Human MXI1
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen MXI1 antibody was raised in mouse using recombinant Human Max Interactor 1

Images

Western Blot analysis of immunized recombinant protein using MXI1 antibody (10R-1598)

Specifications

Host Mouse
Clone MXI1C2a
Isotype IgG1
Method of Purification MXI1 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer MXI1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described.

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Images

  • Western Blot analysis of immunized recombinant protein using MXI1 antibody (10R-1598)

Availability: In stock

Price: $190.00
Size: 50 ug
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