MYD88 antibody (10R-8668)
Mouse monoclonal MYD88 antibody
|Synonyms||Monoclonal MYD88 antibody, Anti-MYD88 antibody, Myeloid differentiation primary response protein MyD88 antibody, MYD88D antibody|
|Immunogen||MYD88 antibody was raised in Mouse using recombinant human MYD88 (1-309aa) purified from E. coli as the immunogen|
Western Blot analysis using MYD88 antibody (10R-8668)
The cell lysates of Raji (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with MYD88 antibody (1:1000).
|Method of Purification||MYD88 antibody was purified by protein-A affinity chromatography|
|Form & Buffer||Supplied in liquid form in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol and 0.02% Sodium Azide|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:1000|
Storage & Safety
|Storage||Can be stored at 4 deg C short term. For long term storage, aliquot and store at -20 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||Myeloid differentiation primary response gene 88 (MYD88) is adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein increases IL-8 transcription. It is involved in IL-18-mediated signaling pathway. MYD88 activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes.|
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