Myeloperoxidase antibody (10R-2080)
Mouse monoclonal Myeloperoxidase antibody
|Synonyms||Monoclonal Myeloperoxidase antibody, Anti-Myeloperoxidase antibody, Myeloperoxidase antibody, MPO antibody, Anti Myeloperoxidase antibody, MPO antibody|
|Immunogen||Myeloperoxidase antibody was raised in Mouse using a purified recombinant fragment of MPO(aa1-193) expressed in E. coli as the immunogen.|
Western Blot analysis using Myeloperoxidase antibody (10R-2080)
Western Blot showing MPO antibody used against truncated Trx-MPO recombinant protein (1),truncated MBP-MPO (aa1-193) recombinant protein (2) and truncated MPO (aa165-745)-hIgGFc transfected CHO-K1 cell lysate (3).
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.|
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