Myostatin antibody (10R-1906)
Mouse monoclonal Myostatin antibody
|Synonyms||Monoclonal Myostatin antibody, Anti-Myostatin antibody, Anti Myostatin antibody, Myostatin antibody, GDF8 antibody, GDF-8 antibody, GDF 8 antibody, GDF-8 antibody, GDF8 antibody, GDF 8 antibody|
|Immunogen||Myostatin antibody was raised in Mouse using a purified recombinant fragment of Myostatin expressed in E. coli as the immunogen.|
Western Blot analysis using Myostatin antibody (10R-1906)
Western Blot showing Myostatin antibody used against truncated Myostatin-His recombinant protein (1).
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Myostatin is a TGF beta family member that acts as an inhibitor of skeletal muscle growth. This muscle-specific cytokine interacts with Activin type I and type II receptors, and suppresses myoblast proliferation by arresting cell-cycle in the G1 phase. Suppression of myostatin activity facilitates muscle formation and may be useful in reducing and/or preventing adiposity and type-2 diabetes. Myostatin activity can be blocked by the Activin-binding protein Follistatin, and by the propeptide of Myostatin.|
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