NCOA3 antibody (10R-2032)
Mouse monoclonal NCOA3 antibody
|Synonyms||Monoclonal NCOA3 antibody, Anti-NCOA3 antibody, NCOA-3, NCOA 3 antibody, CTG26 antibody, NCOA3, ACTR antibody, MGC141848 antibody, SRC3 antibody, RAC3 antibody, Nuclear receptor coactivator 3 antibody, TNRC14 antibody, SR-1c antibody, CAGH16 antibody, TRAM-1 antibody, AIB1 antibody, TNRC16 antibody, pCIP antibody, AIB-1 antibody, NCOA 3, NCOA-3 antibody|
|Immunogen||NCOA3 antibody was raised in Mouse using a purified recombinant fragment of NCOA3(aa1-200) expressed in E. coli as the immunogen.|
Western Blot analysis using NCOA3 antibody (10R-2032)
Western Blot showing NCOA3 antibody used against truncated Trx-NCOA3 recombinant protein (1) and truncated NCOA3 (aa1-200)-hIgGFc transfected CHOK1 cell lysate (2).
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||NCOA3 is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. NCOA3 has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.|
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