NCOR1 antibody (10R-2008)

Mouse monoclonal NCOR1 antibody

Synonyms Monoclonal NCOR1 antibody, Anti-NCOR1 antibody, NCOR 1, NCOR-1, Nuclear receptor co-repressor 1 antibody, Nuclear receptor co-repressor 1 antibody, NCOR-1 antibody, NCOR 1 antibody, NCOR1
Cross Reactivity Human
Applications ELISA, IHC, WB
Immunogen NCOR1 antibody was raised in Mouse using a purified recombinant fragment of NCOR1(aa1-192) expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using NCOR1 antibody (10R-2008)

Immunohistochemical analysis of paraffin-embedded human cerebra (left) and breast carcinoma tissue (right), showing nuclear location with DAB staining using NCOR1 antibody.

Specifications

Host Mouse
Clone 7A7A9
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

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Images

  • Immunohistochemical staining using NCOR1 antibody (10R-2008) | Immunohistochemical analysis of paraffin-embedded human cerebra (left) and breast carcinoma tissue (right), showing nuclear location with DAB staining using NCOR1 antibody.
  • Western Blot analysis using NCOR1 antibody (10R-2008) | Western Blot showing NCOR1 antibody used against truncated Trx-NCOR1 recombinant protein (1).

Availability: In stock

Price: $375.00
Size: 100 ul
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