Nestin antibody (10R-8096)

Mouse monoclonal Nestin antibody

Synonyms Monoclonal Nestin antibody, Anti-Nestin antibody, NES antibody, type VI intermediate filament (IF) protein antibody, Nestin
Cross Reactivity Human
Applications IHC, IHC-F, IHC-P, WB
Immunogen Nestin antibody was raised in Mouse using cloned human nestin conjugated to glutathione S-transferase as the immunogen.

Specifications

Host Mouse
Clone 10C2
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IHC: 1:100-1:200, WB: 1:100-1:1000

General Information

Biological Significance Nestin is a Class IV intermediate filament protein abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. This cytoskeletal protein has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, it is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. These highly specific antibodies to human nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells.

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Availability: In stock

Price: $380.00
Size: 100 ug
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