Neu antibody (10R-N105k)

Mouse monoclonal Neu antibody

Synonyms Monoclonal Neu antibody, Anti-Neu antibody
Cross Reactivity Human, mouse, rat
Applications IHC, IP, WB
Immunogen Neu antibody was raised in mouse using cytoplasmic domain of recombinant human c-erbB-2/HER-2 as the immunogen.

Images

Immunohistochemical staining using Neu antibody (10R-N105k)

Formalin-fixed, paraffin-embedded human breast carcinoma stained with Neu antibody using peroxidase-conjugate and AEC chromogen. Note intense cell membrane staining of tumor cells.

Specifications

Host Mouse
Clone e2-4001
Isotype IgG1
Method of Purification Neu antibody was purified by Protein A chromatography.
Molecular Weight 185 kDa (predicted detection band MW)
Form & Buffer Antibody purified from ascites fluid by protein G chromotography and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
Concentration 0.2 mg/ml

Usage & Assay Information

Usage Recommendations IHC: 1:200-1:400, IP: 2 ug/mg protein lysate, WB: 1-2 ug/ml

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Immunohistochemical staining using Neu antibody (10R-N105k) | Formalin-fixed, paraffin-embedded human breast carcinoma stained with Neu antibody using peroxidase-conjugate and AEC chromogen. Note intense cell membrane staining of tumor cells.

Availability: In stock

Price: $445.00
Size: 100 ug
OR
Shipping
View Our Distributors