Neurokinin B protein (His tag) (80R-1179)
Purified recombinant Human Neurokinin B protein
|Synonyms||TAC3 protein, PRO 1155 protein, NeurokininB protein, ZNEUROK 1., ZNEUROK1 protein, Tachykinin3 protein, Tachykinin3 protein, Neuromedin K protein, Neurokinin B like protein protein, NKNB protein, NKB protein, PreprotachykininB protein, Neurokinin beta protein, Gamma tachykinin 3 protein, Preprotachykinin B protein, Neurokinin B protein protein, PRO1155 protein, NeuromedinK protein, Tachykinin 3 protein, TAC 3 protein|
Coomassie Blue stained SDS-PAGE of Neurokinin B protein (His tag) (80R-1179)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||17-121 amino acids: MGSSHHHHHH SSGLVPRGSH QSFGAVCKEP QEEVVPGGGR SKRDPDLYQL LQRLFKSHSS LEGLLKALSQ ASTDPKESTS PEKRDMHDFF VGLMGKRSVQ PDSPTDVNQE NVPSFGILKY PPRAE|
|Purity||> 95% pure|
|Molecular Weight||13.8 kDa (125aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Neurokinin B, a member of the substance P-related tachykinin family, was previously known to be present in the same hypothalamic neurons as kisspeptin. This protein and its receptor are critical switches of regulator of human puberty, governed by the brain through the release of the hormone GnRH (gonadotropin-releasing hormone) which starts a series of processes that ultimately leads to the production of sex hormones. Many studies suggest new approaches to the pharmacological control of human reproduction and sex hormone-related diseases. Recombinant human Neurokinin B, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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