NKIRAS2 protein (His tag) (80R-2259)
Purified recombinant Human NKIRAS2 Protein (His tag)
|Synonyms||NKIRAS-2, NKIRAS2, NKIRAS 2, NKIRAS 2 protein, kappaB-Ras2 protein, NFKB inhibitor interacting Ras-like 2 protein, NKIRAS-2 protein, KBRAS2 protein|
Coomassie Blue stained SDS-PAGE of NKIRAS2 protein (His tag) (80R-2259)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MGSSHHHHHH SSGLVPRGSH MGSHMGKSCK VVVCGQASVG KTSILEQLLY GNHVVGSEMI ETQEDIYVGS IETDRGVREQ VRFYDTRGLR DGAELPRHCF SCTDGYVLVY STDSRESFQR VELLKKEIDK SKDKKEVTIV VLGNKCDLQE QRRVDPDVAQ HWAKSEKVKL WEVSVADRRS LLEPFVYLAS KMTQPQSKSA FPLSRKNKGS GSLDG|
|Purity||> 90% pure|
|Molecular Weight||24.0 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer, pH 8.0 containing 1mM DTT, 10% glycerol, 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase.|
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