NKX2.5 antibody (10R-1864)
Mouse monoclonal NKX2.5 antibody
|Synonyms||Monoclonal NKX2.5 antibody, Anti-NKX2.5 antibody, CSX antibody, NKX2.5, NKX 2.5 antibody, NKX 2.5 antibody, NKX-2.5 antibody, NK2 transcription factor related locus 5 antibody, NKX 2.5, NKX-2.5 antibody, NKX-2.5|
|Immunogen||NKX2.5 antibody was raised in Mouse using a purified recombinant fragment of human NKX2.5 expressed in E. coli as the immunogen.|
Western Blot analysis using NKX2.5 antibody (10R-1864)
Western Blot showing NKX2.5 antibody used against full-length NKX2.5 (aa1-324)-hIgGFc transfected HEK293 cell lysate (1).
|Method of Purification||NKX2.5 antibody was purified by protein G affinity chromatography.|
|Form & Buffer||Supplied as a liquid in PBS containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||NKX2. 5 is a homeobox-containing transcription factor. This transcription factor functions in cardiac formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.|
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